Details

Autor(en) / Beteiligte

• Demarchi, Luiz Henrique Ferraz
• Bandeira, Larissa Melo
• Taira, Deborah Ledesma
• Zardin, Marina Castilhos Souza Umaki
• Ibanhes, Mary Luizia
• Esposito, Ana Olivia Pascoto
• De Arruda, Larissa Domingues Castilho
• Gonçalves, Crhistinne Cavalheiro Maymone
• Weis-Torres, Sabrina Moreira Dos Santos
• Cesar, Gabriela Alves
• Da Cunha, Rivaldo Venâncio
• Tanaka, Tayana Serpa Ortiz
• Puga, Marco Antonio Moreira
• De Rezende, Grazielli Rocha
• Lopes, Roberta Barbosa
• Uehara, Silvia Naomi de Oliveira
• Pinho, João Renato Rebello
• Carrilho, Flair Jose
• Gomes-Gouvêa, Michele Soares
• Motta-Castro, Ana Rita Coimbra

Titel

Hepatitis B Virus Infection among Japanese Immigrants and Descendants: The Need to Strengthen Preventive and Control Measures

Ist Teil von

• Viruses, 2022-05, Vol.14 (5), p.1085

Ort / Verlag

Switzerland: MDPI AG

Erscheinungsjahr

2022

Quelle

MEDLINE

Beschreibungen/Notizen

• This cross-sectional study aimed to investigate the prevalence and risk factors of Hepatitis B virus infection among Japanese immigrants and their descendants from São Paulo (SP), and to verify the occurrence of occult hepatitis B and coinfection with HCV, Delta, and HTLV. All samples ( = 2.127) were tested for HBV serological markers by electrochemiluminescence. HBsAg and/or total anti-HBc positive samples were tested for HBV DNA by real-time PCR, and genotyped by sequencing using the Sanger methodology. The prevalence rate of HBV exposure was 13.4% (CI 95%: 11.9-14.9%), and 22 (1.1%) were HBsAg positive. A high rate of susceptibility to HBV infection was found (67.4%; CI 95%: 65.4-69.4%). In contrast, only 19.2% (CI 95%: 17.6-20.9%) presented a serological profile analogous to that elicited by Hepatitis B vaccination. HBV isolates ( = 8) were classified as genotypes HBV/B1 (62.5%), HBV/C2 (12.5%), HBV/F1b (12.5%), and HBV/A1 (12.5%). Hepatitis B vaccination strategies and educational measures to control this infection should be considered.