Details

Autor(en) / Beteiligte

• Hyun, Dong-gon
• Lee, Su Yeon
• Ahn, Jee Hwan
• Huh, Jin Won
• Hong, Sang-Bum
• Koh, Younsuck
• Lim, Chae-Man
• Oh, Dong Kyu
• Suh, Gee Young
• Jeon, Kyeongman
• Ko, Ryoung-Eun
• Cho, Young-Jae
• Lee, Yeon Joo
• Lim, Sung Yoon
• Park, Sunghoon
• Heo, Jeongwon
• Lee, Jae-myeong
• Kim, Kyung Chan
• Chang, Youjin
• Lee, Sang-Min
• Hong, Suk-Kyung
• Cho, Woo Hyun
• Kwak, Sang Hyun
• Lee, Heung Bum
• Ahn, Jong-Joon
• Seong, Gil Myeong
• Lee, Song-I
• Park, Tai Sun
• Lee, Su Hwan
• Choi, Eun Young
• Moon, Jae Young

Titel

Mortality of patients with hospital-onset sepsis in hospitals with all-day and non-all-day rapid response teams: a prospective nationwide multicenter cohort study

Ist Teil von

• Critical care (London, England), 2022-09, Vol.26 (1), p.1-280, Article 280

Ort / Verlag

London: BioMed Central Ltd

Erscheinungsjahr

2022

Quelle

Electronic Journals Library

Beschreibungen/Notizen

• Abstract Background Hospital-onset sepsis is associated with a higher in-hospital mortality rate than community-onset sepsis. Many hospitals have implemented rapid response teams (RRTs) for early detection and timely management of at-risk hospitalized patients. However, the effectiveness of an all-day RRT over a non-all-day RRT in reducing the risk of in-hospital mortality in patient with hospital-onset sepsis is unclear. We aimed to determine the effect of the RRT’s operating hours on in-hospital mortality in inpatient patients with sepsis. Methods We conducted a nationwide cohort study of adult patients with hospital-onset sepsis prospectively collected from the Korean Sepsis Alliance (KSA) Database from 16 tertiary referral or university-affiliated hospitals in South Korea between September of 2019 and February of 2020. RRT was implemented in 11 hospitals, of which 5 (45.5%) operated 24-h RRT (all-day RRT) and the remaining 6 (54.5%) had part-day RRT (non-all-day RRT). The primary outcome was in-hospital mortality between the two groups. Results Of the 405 patients with hospital-onset sepsis, 206 (50.9%) were admitted to hospitals operating all-day RRT, whereas 199 (49.1%) were hospitalized in hospitals with non-all-day RRT. A total of 73 of the 206 patients in the all-day group (35.4%) and 85 of the 199 patients in the non-all-day group (42.7%) died in the hospital ( P  = 0.133). After adjustments for co-variables, the implementation of all-day RRT was associated with a significant reduction in in-hospital mortality (adjusted odds ratio 0.57; 95% confidence interval 0.35–0.93; P  = 0.024). Conclusions In comparison with non-all-day RRTs, the availability of all-day RRTs was associated with reduced in-hospital mortality among patients with hospital-onset sepsis.