Details

Autor(en) / Beteiligte

• De Luca, Chiara
• Krauke, Yannick
• Stephan, Svea
• Greco, Giorgia
• Compagnin, Greta
• Buratti, Alessandro
• Cavazzini, Alberto
• Catani, Martina
• Felletti, Simona

Titel

Green cannabigerol purification through simulated moving bed chromatography

Ist Teil von

• Green Analytical Chemistry, 2023-09, Vol.6, p.100066, Article 100066

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• •Minor cannabinoids are gaining popularity thanks to their positive properties.•Cannabinoids (e.g. CBG) must be purified in order to perform clinical tests.•Available purification methods are unsustainable and make use of toxic solvents.•SMB operated with green solvents can boost process performance and greenness.•The proposed application allows to achieve a THC-free CBG extract at 97% purity. [Display omitted] Cannabigerol (CBG) is a minor cannabinoid present in Cannabis sativa L. This molecule is gaining increasing popularity thanks to its antibacterial, antimicrobial, antidepressant and antitumoral properties. In parallel, there is growing attention towards the search of efficient, cost-effective, rapid, high-throughput, and green purification techniques. In this work, CBG has been purified from a real cannabis extract by means of simulated moving bed chromatography. The proposed application is very promising, allowing to achieve a CBG extract free of tetrahydrocannabinol (a psychoactive cannabinoid) with 100% recovery and 97% final purity by using a faster and greener method if compared to traditionally used ones.