Details

Autor(en) / Beteiligte

• Sheng, Xiao
• Li, Chen
• Wang, Zhonghan
• Xu, Yu
• Sun, Yang
• Zhang, Weimin
• Liu, He
• Wang, Jincheng

Titel

Advanced applications of strontium-containing biomaterials in bone tissue engineering

Ist Teil von

• Materials today bio, 2023-06, Vol.20, p.100636-100636, Article 100636

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Strontium (Sr) and strontium ranelate (SR) are commonly used therapeutic drugs for patients suffering from osteoporosis. Researches have showed that Sr can significantly improve the biological activity and physicochemical properties of materials in vitro and in vivo. Therefore, a large number of strontium containing biomaterials have been developed for repairing bone defects and promoting osseointegration. In this review, we provide a comprehensive overview of Sr-containing biomaterials along with the current state of their clinical use. For this purpose, the different types of biomaterials including calcium phosphate, bioactive glass, and polymers are discussed and provided future outlook on the fabrication of the next-generation multifunctional and smart biomaterials. [Display omitted] •Reviewed the different mechanisms of strontium promoting osteogenesis•Different strontium containing biomaterials in bone tissue engineering•Application potential of co-doping of strontium with other therapeutic ions materials•Future research directions regarding strontium-containing biomaterials are prospected.