Details

Autor(en) / Beteiligte

• Shinde, Pallavi
• Mohan, Loganathan
• Kumar, Amogh
• Dey, Koyel
• Maddi, Anjali
• Patananan, Alexander N
• Tseng, Fan-Gang
• Chang, Hwan-You
• Nagai, Moeto
• Santra, Tuhin Subhra

Titel

Current Trends of Microfluidic Single-Cell Technologies

Ist Teil von

• International journal of molecular sciences, 2018-10, Vol.19 (10), p.3143

Ort / Verlag

Switzerland: MDPI

Erscheinungsjahr

2018

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• The investigation of human disease mechanisms is difficult due to the heterogeneity in gene expression and the physiological state of cells in a given population. In comparison to bulk cell measurements, single-cell measurement technologies can provide a better understanding of the interactions among molecules, organelles, cells, and the microenvironment, which can aid in the development of therapeutics and diagnostic tools. In recent years, single-cell technologies have become increasingly robust and accessible, although limitations exist. In this review, we describe the recent advances in single-cell technologies and their applications in single-cell manipulation, diagnosis, and therapeutics development.