Details

Autor(en) / Beteiligte

• Li, Nan
• Qian, Qiliu
• Ouyang, Jun
• Hu, Mingyue
• Liu, Juan
• Wu, Hailu
• Shi, Ruihua
• Zheng, Shiya

Titel

Clinical value of serum polyunsaturated fatty acids in patients with gastric polyps

Ist Teil von

• PeerJ (San Francisco, CA), 2024-05, Vol.12, p.e17413-e17413, Article e17413

Ort / Verlag

United States: PeerJ Inc

Erscheinungsjahr

2024

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Polyunsaturated fatty acids (PUFAs) are vital nutrients in human physiology and are implicated in various chronic diseases. However, the relationship between PUFAs and gastric polyps remains unclear. This study employed liquid chromatography-tandem mass spectrometry (LC-MS/MS) to assess PUFA levels in the serum of 350 patients, along with analyzing the ω-6 to ω-3 ratio. The results revealed significant differences in the levels of C16:1, C18:1, C18:2, α-C18:3, γ-C18:3, C20:1, C20:4, C20:5, ω-3-C22:5, ω-6-C22:5, and C22:6, as well as ω-6 to ω-3 ratio between the control and gasteic polyp groups. Moreover, setting the threshold for ω-6: ω-3 at 10 revealed a close correlation between polyp occurrence and this ratio. These findings suggest that PUFAs and the ω-6 to ω-3 ratio hold promise as potential early screening markers for gastric polyps. However, further research is imperative to elucidate the underlying mechanisms and therapeutic potential of PUFAs in managing gastric polyps.