Details

Autor(en) / Beteiligte

• van der Vaart, Jelte
• Lamers, Mart M.
• Haagmans, Bart L.
• Clevers, Hans

Titel

Advancing lung organoids for COVID-19 research

Ist Teil von

• Disease models & mechanisms, 2021-06, Vol.14 (6)

Ort / Verlag

Cambridge: The Company of Biologists Ltd

Erscheinungsjahr

2021

Link zum Volltext

Quelle

Elektronische Zeitschriftenbibliothek - Freely accessible e-journals

Beschreibungen/Notizen

• ABSTRACT The COVID-19 pandemic has emphasised the need to develop effective treatments to combat emerging viruses. Model systems that poorly represent a virus' cellular environment, however, may impede research and waste resources. Collaborations between cell biologists and virologists have led to the rapid development of representative organoid model systems to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We believe that lung organoids, in particular, have advanced our understanding of SARS-CoV-2 pathogenesis, and have laid a foundation to study future pandemic viruses and develop effective treatments.