International journal of molecular sciences, 2022-11, Vol.23 (23), p.14566
2022
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Details
- Autor(en) / Beteiligte
- Titel
- Laser Capture Microdissection: A Gear for Pancreatic Cancer Research
- Ist Teil von
- International journal of molecular sciences, 2022-11, Vol.23 (23), p.14566
- Ort / Verlag
- Switzerland: MDPI AG
- Erscheinungsjahr
- 2022
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The advancement in molecular techniques has been attributed to the quality and significance of cancer research. Pancreatic cancer (PC) is one of the rare cancers with aggressive behavior and a high mortality rate. The asymptomatic nature of the disease until its advanced stage has resulted in late diagnosis as well as poor prognosis. The heterogeneous character of PC has complicated cancer development and progression studies. The analysis of bulk tissues of the disease was insufficient to understand the disease, hence, the introduction of the single-cell separating technique aided researchers to decipher more about the specific cell population of tumors. This review gives an overview of the Laser Capture Microdissection (LCM) technique, one of the single-cell separation methods used in PC research.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1422-0067, 1661-6596eISSN: 1422-0067DOI: 10.3390/ijms232314566Titel-ID: cdi_doaj_primary_oai_doaj_org_article_ba6efb0cdec04562936bd19331d17649
- Format
- –
- Schlagworte
- Biomarkers, Cancer research, Carcinoma, Pancreatic Ductal - pathology, Fibroblasts, Gene amplification, Genomes, Humans, hypoxia, intraductal papillary mucinous neoplasm (IPMN), Laser Capture Microdissection, Laser Capture Microdissection (LCM), Lasers, Medical prognosis, Medical research, metastasis, Mutation, Pancreas - pathology, Pancreatic cancer, Pancreatic Neoplasms, Pancreatic Neoplasms - pathology, Proteins, Review, single-cell separation, Tumors