Details

Autor(en) / Beteiligte

• Cui, Yuwen
• Yang, Xinjie
• Zhang, Dongdong
• Li, Yuze
• Zhang, Li
• Song, Bei
• Yue, Zhenggang
• Song, Xiaomei
• Tang, Haifeng

Titel

Steroidal Constituents from Roots and Rhizomes of Smilacina japonica

Ist Teil von

• Molecules (Basel, Switzerland), 2018-03, Vol.23 (4), p.798

Ort / Verlag

Switzerland: MDPI AG

Erscheinungsjahr

2018

Link zum Volltext

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• Four new steroidal constituents ( - ) along with two known steroidal glycosides ( and ) were isolated from the roots and rhizomes of . Analysis of their physicochemical properties and spectroscopic profiles identified the compounds as (25 )-5 -spirostan-9(11)-en-3β, 17 -diol ( ); (25 )-5 -spirostan-9(11)-en-3β, 12β-diol ( ); (25 )-5 -spirostan-9(11)-en-3β, 17 -diol-3- -β-d-glucopyranoside ( ); (25 )-5 -spirostan-9(11)-en-3β, 17 -diol-3- -β-d-glucopyranosyl-(1→2)-[β-d-glucopyranosyl-(1→3)]-β-d-galactopyranoside ( ); japonicoside B ( ); and japonicoside C ( ). All six compounds showed cytotoxic activity against SMMC-7712, Bel-7402, A549, H460, and K562 human cancer cells.