Details

Autor(en) / Beteiligte

• Adams, Yussif
• Ofori, Emmanuel Kwaku
• Asare-Anane, Henry
• Amanquah, Seth D
• Ababio, Grace Korkor
• Abendau, Emmanuel
• Nabia, Richard

Titel

Adipocytokines in obese Ghanaian subjects with or without type 2 diabetes

Ist Teil von

• BMC research notes, 2018-02, Vol.11 (1), p.109-109, Article 109

Ort / Verlag

England: BioMed Central Ltd

Erscheinungsjahr

2018

Quelle

springer (창간호~2014)

Beschreibungen/Notizen

• This study aimed to evaluate serum leptin and high sensitivity C-reactive protein (hsCRP) concentrations in obese Ghanaians with or without type 2 diabetes and to find out the extent to which their levels are influenced by underlying disorders. Obese subjects with type 2 diabetes had lower leptin but higher hsCRP levels compared with obese non-diabetic controls. There were negative correlations within the control group for glucose vs % muscle mass (r = - 0.378, p = 0.016), leptin vs % muscle mass (r = - 0.555, p = 0.001) and within the obese diabetic group for leptin vs % muscle mass (r = - 0.602, p = 0.001). Obese persons without diabetes were about three times more likely to have higher leptin levels compared with their obese diabetic counterparts (Odds ratio = 3.315, p < 0.001). Obese females independently had a tenfold increase in leptin levels compared with obese males.