Molecules (Basel, Switzerland), 2018-07, Vol.23 (7), p.1665
2018
Details
- Autor(en) / Beteiligte
- Titel
- Interleukin-33: Its Emerging Role in Allergic Diseases
- Ist Teil von
- Molecules (Basel, Switzerland), 2018-07, Vol.23 (7), p.1665
- Ort / Verlag
- Switzerland: MDPI AG
- Erscheinungsjahr
- 2018
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world. Recently, interleukin-33 (IL-33) has been found to play an important role in these refractory disorders, mainly by inducing T helper (Th) 2 immune responses. This article reviews the mobilization and biological function of IL-33 in allergic disorders, providing novel insights for addressing these hypersensitive conditions.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1420-3049eISSN: 1420-3049DOI: 10.3390/molecules23071665Titel-ID: cdi_doaj_primary_oai_doaj_org_article_b32b65febb57466aab9ce652e5d04305
- Format
- –
- Schlagworte
- Allergic diseases, Allergic rhinitis, asthma, Atopic dermatitis, Cytokines, Dermatitis, Eczema, Food allergies, Histamine, Humans, Hypersensitivity - immunology, Hypersensitivity - psychology, Immune response, Interleukin-1 Receptor-Like 1 Protein - metabolism, interleukin-33, Interleukin-33 - metabolism, Keratoconjunctivitis, Quality of Life, Review, Rhinitis, Rhinosinusitis, Signal Transduction, target therapy, Th2 Cells - immunology, Th2-type immunity, Up-Regulation