Details

Autor(en) / Beteiligte

• Horgan, Denis
• Van den Bulcke, Marc
• Malapelle, Umberto
• Troncone, Giancarlo
• Normanno, Nicola
• Capoluongo, Ettore D.
• Prelaj, Arsela
• Rizzari, Carmelo
• Trapani, Dario
• Singh, Jaya
• Kozaric, Marta
• Longshore, John
• Ottaviano, Manuel
• Boccia, Stefania
• Pravettoni, Gabriella
• Cattaneo, Ivana
• Malats, Núria
• Buettner, Reinhard
• Lekadir, Karim
• de Lorenzo, Francesco
• Hofman, Paul
• De Maria, Ruggero

Titel

Tackling the implementation gap for the uptake of NGS and advanced molecular diagnostics into healthcare systems

Ist Teil von

• Heliyon, 2024-01, Vol.10 (1), p.e23914-e23914, Article e23914

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Next-generation sequencing (NGS) and liquid biopsy (LB) showed positive results in the fight against different cancer types. This paper aims to assess the uptake of advanced molecular diagnostics/NGS for quick and efficient genetic profiles of tumour cells. For that purpose, the European Alliance for Personalised Medicine conducted a series of expert interviews to ascertain the current status across member states. One stakeholder meeting was additionally conducted to prioritize relevant factors by stakeholders. Seven common pillars were identified, and twenty-five measures were defined based on these pillars. Results showed that a multi-faceted approach is necessary for successful NGS implementation and that regional differences may be influenced by healthcare policies, resources, and infrastructure. It is important to consider different correlations when interpreting the results and to use them as a starting point for further discussion.