Details

Autor(en) / Beteiligte

• Venceslau, Marianna Tavares
• Lebreiro, Giuliana Pucarelli
• Leitão, Gabrielly de Souza
• Alves, Brenda Klemm Arci Mattos de Freitas
• Gouvea, Luane Abdalla
• Pastura, Giuseppe Mario Carmine
• Anachoreta, Thiago Dias
• da Rocha, Regina Cláudia Silva
• Maciel, Fernanda Queiroz
• Cordeiro, Catherine Crespo
• Castiñeiras, Terezinha Marta Pereira Pinto
• Abreu, Thalita Fernandes
• Frota, Ana Cristina Cisne
• Varella, Rafael Brandão
• Guimarães, Maria Angelica Arpon Marandino
• Hofer, Cristina Barroso

Titel

Neurological Manifestations Associated With SARS-CoV-2 in Children: A Case Series

Ist Teil von

• Journal of central nervous system disease, 2022-05, Vol.14, p.11795735221102740-11795735221102740

Ort / Verlag

London, England: SAGE Publications

Erscheinungsjahr

2022

Link zum Volltext

Quelle

EZB-FREE-00999 freely available EZB journals

Beschreibungen/Notizen

• Neurological manifestations of COVID-19 may affect both central and peripheral nervous systems. Unlike in adults, in whom majority of severe cases derive from respiratory complications, neurological involvement is one of the main causes of severe COVID-19 in children. This study aimed to detect viral respiratory pathogens, mainly SARS-CoV-2, in nasopharynx and cerebrospinal fluid samples utilizing qRT-PCR (TaqMan) in a pediatric population in Brazil. We evaluated four children with neurological symptoms and laboratory-confirmed SARS-CoV-2 infection: three presenting with meningoencephalitis and one presenting with Guillain-Barré syndrome. All four patients had mild respiratory symptoms. SARS-CoV-2 RNA was identified in two cerebrospinal fluid samples. SARS-CoV-2 involvement should be considered for differential diagnosis in pediatric cases presenting neurological alterations even if symptoms such as headache, anosmia, or dizziness are absent.