Pathogens (Basel), 2024-04, Vol.13 (4), p.340
2024
Details
- Autor(en) / Beteiligte
- Titel
- Descriptive Epidemiology of Pathogens Associated with Acute Respiratory Infection in a Community-Based Study of K-12 School Children (2015-2023)
- Ist Teil von
- Pathogens (Basel), 2024-04, Vol.13 (4), p.340
- Ort / Verlag
- Switzerland: MDPI AG
- Erscheinungsjahr
- 2024
- Link zum Volltext
- Quelle
- EZB Free E-Journals
- Beschreibungen/Notizen
- School-based outbreaks often precede increased incidence of acute respiratory infections in the greater community. We conducted acute respiratory infection surveillance among children to elucidate commonly detected pathogens in school settings and their unique characteristics and epidemiological patterns. The ORegon CHild Absenteeism due to Respiratory Disease Study (ORCHARDS) is a longitudinal, laboratory-supported, school-based, acute respiratory illness (ARI) surveillance study designed to evaluate the utility of cause-specific student absenteeism monitoring for early detection of increased activity of influenza and other respiratory viruses in schools from kindergarten through 12th grade. Eligible participants with ARIs provided demographic, epidemiologic, and symptom data, along with a nasal swab or oropharyngeal specimen. Multipathogen testing using reverse-transcription polymerase chain reaction (RT-PCR) was performed on all specimens for 18 respiratory viruses and 2 atypical bacterial pathogens ( and ). Between 5 January 2015 and 9 June 2023, 3498 children participated. Pathogens were detected in 2455 of 3498 (70%) specimens. Rhinovirus/enteroviruses (36%) and influenza viruses A/B (35%) were most commonly identified in positive specimens. Rhinovirus/enteroviruses and parainfluenza viruses occurred early in the academic year, followed by seasonal coronaviruses, RSV, influenza viruses A/B, and human metapneumovirus. Since its emergence in 2020, SARS-CoV-2 was detected year-round and had a higher median age than the other pathogens. A better understanding of the etiologies, presentations, and patterns of pediatric acute respiratory infections can help inform medical and public health system responses.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 2076-0817eISSN: 2076-0817DOI: 10.3390/pathogens13040340Titel-ID: cdi_doaj_primary_oai_doaj_org_article_9f4a4c4aaa454b2cbd687da7599d03c5
- Format
- –
- Schlagworte
- Absenteeism, acute respiratory infection, Bacteria, Pathogenic, Bacterial pneumonia, Causes of, Children, Children & youth, Coronaviruses, COVID-19, Development and progression, Disease control, Disease transmission, Elementary school students, Enrollments, Enteroviruses, Epidemics, Epidemiology, Families & family life, Genetic aspects, Health aspects, Health surveillance, Households, Identification and classification, Illnesses, Influenza, Influenza viruses, Kindergarten, Laboratories, Medical research, Medical supplies, Medicine, Experimental, Nucleotide sequence, Orthomyxoviridae, Parainfluenza, Pathogenic microorganisms, Pathogens, Pediatric respiratory diseases, Pediatrics, Pneumonia, Polymerase chain reaction, Public health, Respiratory diseases, Respiratory disorders, respiratory illness, Respiratory syncytial virus, Respiratory tract infection, respiratory viruses, Rhinovirus, School districts, school-based surveillance, Schools, Severe acute respiratory syndrome coronavirus 2, Sexually transmitted diseases, Statistics, STD, Students, Surveillance, Transcription, United States, Viral diseases, Viruses