Emerging infectious diseases, 2009-12, Vol.15 (12), p.1988-1990
2009
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Details
- Autor(en) / Beteiligte
- Titel
- CTX-M beta-lactamase production and virulence of Escherichia coli K1
- Ist Teil von
- Emerging infectious diseases, 2009-12, Vol.15 (12), p.1988-1990
- Ort / Verlag
- United States: Centers for Disease Control and Prevention
- Erscheinungsjahr
- 2009
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- We report a patient with neonatal meningitis caused by a CTX-M-1-producing Escherichia coli K1 strain. The influence of CTX-M production on virulence was investigated in cell culture and a newborn mouse model of meningitis. CTX-M production had no influence on virulence but was a major factor in clinical outcome.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1080-6040eISSN: 1080-6059DOI: 10.3201/eid1512.090928Titel-ID: cdi_doaj_primary_oai_doaj_org_article_9e9b6f68a3e34fbaa2679c4f80bd8d32
- Format
- –
- Schlagworte
- Adult, Animals, antimicrobial resistance, beta-Lactamases - biosynthesis, CTX-M, Dispatch, Escherichia coli, Escherichia coli - enzymology, Escherichia coli - pathogenicity, extended-spectrum β-lactamase, Female, Humans, Infant, Newborn, meningitis, Meningitis, Bacterial - etiology, Mice, Pregnancy, Virulence