Details

Autor(en) / Beteiligte

• Almehizia, Abdulrahman A.
• Al-Omar, Mohamed A.
• Al-Obaid, Abdulrahman M.
• Naglah, Ahmed M.
• Bhat, Mashooq A.
• Ghabbour, Hazem A.
• Khatab, Tamer K.
• Hassan, Ashraf S.

Titel

Synthesis and characterization of curcumin-encapsulated loaded on carboxymethyl cellulose with docking validation as α-amylase and α-glucosidase inhibitors

Ist Teil von

• Polish journal of chemical technology, 2024-09, Vol.26 (3), p.63-69

Ort / Verlag

Szczecin: Sciendo

Erscheinungsjahr

2024

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• In reaction to the expanding predominance of diabetes mellitus, curcumin nanoparticles stacked on carboxymethyl cellulose (CMC) composite were effectively synthesized, characterized, and examined utilizing UV/Vis and FTIR spectroscopy combined with transmission electron microscopy (TEM). The bioactivity of curcumin (Cur), carboxymethyl cellulose (CMC), and curcumin nanoparticles stacked with carboxymethyl cellulose (CUR-CMC) was tried through atomic docking approval as an α-amylase and α-glucosidase inhibitor. The conclusion illustrated that the curcumin-supported CMC is more potent than CUR itself self the validation presented is compared with acarbose as a reference molecule and then CUR-CMC can presented as promising in curing hyperglycemia by decreasing the absorption of glucose.