Details

Autor(en) / Beteiligte

• Rabbani, Malik Anas
• Memon, Ghulam Murtaza
• Ahmad, Bushra
• Memon, Shehla
• Tahir, Syeda Anjala
• Tahir, Shumaila

Titel

Percutaneous renal biopsy results: a retrospective analysis of 511 consecutive cases

Ist Teil von

• Saudi journal of kidney diseases and transplantation, 2012-05, Vol.23 (3), p.614-618

Ort / Verlag

Saudi Arabia: Medknow Publications and Media Pvt. Ltd

Erscheinungsjahr

2012

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• To determine the patterns of the prevalent glomerulonephritis (GN) in our region, we studied the results of 511 consecutive renal biopsies performed on patients with proteinuria, hematuria and mild to moderate renal impairment at the Aga Khan University Hospital during a period of 18 years from January 1990 to December 2008. Primary glomerular disease accounted for two-thirds of the glomerular diseases, which in turn constituted 49% of all renal biopsies. The most common histological lesion was membranoproliferative disease (28%). Membranous GN was the second most common lesion (19%), followed by minimal change disease (16%) and focal segmental GN (11%). Secondary glomerular disease comprised 30% of glomerular diseases (21% of all the renal biopsies), with lupus nephritis forming the most common lesion (34%) followed by amyloidosis (22%), diabetic nephropathy (10%), Wagener's granulomatosus and post-infectious GN (9% each). Tubulointerstitial diseases accounted for 16% of all the renal biopsies. We conclude that there exists a wide variability in the different categories of primary and secondary glomerular diseases in our region as compared with different parts of the world. Future studies should be directed to analyze the causes for these variations.