Details

Autor(en) / Beteiligte

• Khalilian, Mohammad Reza
• Ziaratban, Mehdi
• Alizadeh, Parinaz
• Norouzi, Ali Reza
• Shirvani, Armin

Titel

Comparison of QT dispersion before and after PDA device closure in pediatrics

Ist Teil von

• Annals of noninvasive electrocardiology, 2022-05, Vol.27 (3), p.e12945-n/a

Ort / Verlag

United States: John Wiley & Sons, Inc

Erscheinungsjahr

2022

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Background Numerous studies have shown that QT dispersion (QTd) can be a suitable criterion for risk assessment of arrhythmia in patients with congenital heart disease. Pulmonary arterial hypertension (PAH) increases the risk of cardiac arrhythmia by changing ventricular repolarization homogeneity. In this study, we assessed QTd changes after PDA device closure and the effect of PAH on these changes. Methods Between October 2018 and March 2021, 97 patients (48 males; 49 females; mean age 31.36 ± 4.26 months; range 3 months to 14 years) who satisfied the primary inclusion criteria and did not meet the exclusion criteria and underwent PDA device closure intervention were included in the study. Echocardiography was performed before the procedure. QT corrected (QTc), and QTd and PR intervals were measured according to the patients’ standard 12‐lead ECGs in two periods, preoperative (1 day) and after (3 months). Results In the general group, QTc and QTd decreased significantly after PDA closure. Based on our classification of the patients in two groups of high PAP and normal PAP, the three parameters QTc, QTd, and PR interval were assessed separately in the two groups. All three parameters decreased significantly in the normal PAP and high PAP groups. Conclusions However, a left‐to‐right shunt through the patent ductus arteriosus can affect ventricular repolarization; this effect seems to be particularly more significant when there is pulmonary hypertension. This study was conducted on 97 pediatric patients with PDA who candidate for PDA device closure. The patients were divided into two normal and high PAP groups based on measurement of pulmonary pressure in cardiac catheterization (67 patients were identified as the normal PAP group and 30 patients as the high PAP group). ECG findings (PR interval, QT corrected, and QT dispersion) were assessed before and after PDA device closure.