Details

Autor(en) / Beteiligte

• Hazra, Druti
• Siddalingaiah, Nayana
• Gupta, Nitin
• Chawla, Kiran
• Prabhu, A Ravindra
• Datta, Divya
• Khader, Nisha
• Swaminathan, Shilna Muttickal

Titel

COVID-19 and tuberculosis coinfection: A case-control study from a tertiary care center in South India

Ist Teil von

• Journal of family medicine and primary care, 2023-12, Vol.12 (12), p.3200-3203

Ort / Verlag

India: Medknow Publications and Media Pvt. Ltd

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Electronic Journals Library

Beschreibungen/Notizen

• Coronavirus disease 2019 (COVID-19) and tuberculosis (TB), are presently the major infectious diseases imposing a consequential public health threat and their coinfection has a significant impact on the outcome. To evaluate the clinical features and outcomes of COVID-19-TB coinfected cases compared to solely COVID-19-infected cases. A retrospective observational study was conducted between August 1, 2020, to February 28, 2022, at a tertiary care hospital. In this case-control study, an equal number of gender-age-matched COVID-19 and TB coinfected patients and COVID-19 cases without TB were included using simple random sampling. The data was analyzed using SPSS v 26. Categorical variables were compared using the Chi-square test, and an independent -test or Mann-Whitney U test was applied for the quantitative variables in the univariate analysis. A -value of less than 0.05 was considered significant. A total of 27 patients were included in each group. Upper lobe involvement (44%) and pleural effusion (22%) were significantly more common in TB-COVID-19 cases when compared to the control group (7% and 4%, respectively; < 0.05). Moreover, median levels of C-reactive protein and ferritin were significantly higher in TB-COVID-19 coinfection. Chest radiology and a higher level of certain biomarkers like C-reactive protein and ferritin can help to suspect TB in COVID-19 patients and vice-versa.