Details

Autor(en) / Beteiligte

• Rebecchi, Marco
• Panattoni, Germana
• Edoardo, Bressi
• Ruvo, Ermenegildo
• Sciarra, Luigi
• Politano, Alessandro
• Sgueglia, Marianna
• Ricagni, Chiara
• Verbena, Sara
• Crescenzi, Cinzia
• Sangiorgi, Catia
• Borrelli, Alessio
• De Luca, Lucia
• Scarà, Antonio
• Grieco, Domenico
• Jacomelli, Ilaria
• Martino, Annamaria
• Calò, Leonardo

Titel

Atrial fibrillation and autonomic nervous system: A translational approach to guide therapeutic goals

Ist Teil von

• Journal of arrhythmia, 2021-04, Vol.37 (2), p.320-330

Ort / Verlag

Japan: John Wiley & Sons, Inc

Erscheinungsjahr

2021

Quelle

EZB-FREE-00999 freely available EZB journals

Beschreibungen/Notizen

• The autonomic nervous system (ANS) is known to play an important role in the genesis and maintenance of atrial fibrillation (AF). Biomolecular and genetic mechanisms, anatomical knowledges with recent diagnostic techniques acquisitions, both invasive and non‐invasive, have enabled greater therapeutic goals in patients affected by AF related to ANS imbalance. Catheter ablation of ganglionated plexi (GP) in the left and right atrium has been proposed in varied clinical conditions. Moreover interesting results arise from renal sympathetic denervation and vagal nerve stimulation. Despite all this, in the scenario of ANS modulation translational strategies we necessary must consider the treatment or correction of dynamic factors such as obesity, obstructive sleep apnea, lifestyle, food, and stress. Finally, new antiarrhythmic drugs, gene therapy and “ablatogenomic” could be represent exciting future therapeutic perspectives. Cardioneuroablation and cardioneuromodulation for patients affected by AF related to ANS imbalance.