International journal of molecular sciences, 2017-09, Vol.18 (10), p.2034
2017
Details
- Autor(en) / Beteiligte
- Titel
- New Insights into the Role of Inflammation in the Pathogenesis of Atherosclerosis
- Ist Teil von
- International journal of molecular sciences, 2017-09, Vol.18 (10), p.2034
- Ort / Verlag
- Switzerland: MDPI AG
- Erscheinungsjahr
- 2017
- Link zum Volltext
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of lipids, smooth muscle cell proliferation, cell apoptosis, necrosis, fibrosis, and local inflammation. Immune and inflammatory responses have significant effects on every phase of atherosclerosis, and increasing evidence shows that immunity plays a more important role in atherosclerosis by tightly regulating its progression. Therefore, understanding the relationship between immune responses and the atherosclerotic microenvironment is extremely important. This article reviews existing knowledge regarding the pathogenesis of immune responses in the atherosclerotic microenvironment, and the immune mechanisms involved in atherosclerosis formation and activation.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1422-0067, 1661-6596eISSN: 1422-0067DOI: 10.3390/ijms18102034Titel-ID: cdi_doaj_primary_oai_doaj_org_article_8b40d29fbb3d488ba91f146aee1f8b77
- Format
- –
- Schlagworte
- Animals, Apoptosis, Apoptosis - physiology, Arteriosclerosis, Atherosclerosis, Atherosclerosis - immunology, Atherosclerosis - metabolism, Atherosclerosis - pathology, atherosclerotic immunity, atherosclerotic microenvironment, Cell growth, Cell proliferation, Cell Proliferation - physiology, Fibrosis, Humans, Immune response, Immunity, Inflammation, Inflammation - immunology, Inflammation - metabolism, Inflammation - pathology, Lipids, macrophage, Macrophages - metabolism, oxidative stress, Oxidative Stress - physiology, Pathogenesis, Review, Smooth muscle