Details

Autor(en) / Beteiligte

• de Paula, Vanessa Salete
• Milagres, Flavio Augusto Pádua
• Oliveira, Guilherme de Macêdo
• Miguel, Juliana Custódio
• Cruz, Helena Medina
• Scalioni, Leticia de Paula
• Marques, Vanessa Alves
• Magalhães, Monica de Avelar Figueiredo Mafra
• Romão, Anselmo Rocha
• Gracie, Renata
• Villar, Livia Melo

Titel

High prevalence of hepatitis A in indigenous population in north Brazil

Ist Teil von

• BMC research notes, 2020-09, Vol.13 (1), p.458-458, Article 458

Ort / Verlag

England: BioMed Central Ltd

Erscheinungsjahr

2020

Quelle

Electronic Journals Library

Beschreibungen/Notizen

• Little is known about hepatitis A virus (HAV) prevalence in indigenous communities. This study aims to evaluate the prevalence of HAV in indigenous community compared to urban population located at Western Amazon in Brazil. A total of 872 serum samples were obtained from 491 indigenous and 381 non indigenous individuals aging 0 to 90 years. Samples were tested for total and IgM anti-HAV and positive IgM samples were tested for HAV RNA. The overall prevalence of total anti-HAV was 87%, increased according age showing 100% of prevalence in those aging more than 30 years (p < 0.0001) and it was similar among indigenous and urban population. Total anti-HAV prevalence varied between tribes (p < 0.0001) and urban sites (p = 0.0014) and spatial distribution showed high prevalence in homes that received up to 100 dollars. IgM anti-HAV prevalence was 1.7% with predominance in males, those aging more than 41 years. No HAV RNA was detected. In conclusion, high overall anti-HAV prevalence was found in indigenous communities in North Brazil demonstrating the importance of universal vaccination in this group.