Genome Biology, 2017-05, Vol.18 (1), p.101-101, Article 101
2017
Details
- Autor(en) / Beteiligte
- Titel
- Millstone: software for multiplex microbial genome analysis and engineering
- Ist Teil von
- Genome Biology, 2017-05, Vol.18 (1), p.101-101, Article 101
- Ort / Verlag
- England: BioMed Central
- Erscheinungsjahr
- 2017
- Link zum Volltext
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- Inexpensive DNA sequencing and advances in genome editing have made computational analysis a major rate-limiting step in adaptive laboratory evolution and microbial genome engineering. We describe Millstone, a web-based platform that automates genotype comparison and visualization for projects with up to hundreds of genomic samples. To enable iterative genome engineering, Millstone allows users to design oligonucleotide libraries and create successive versions of reference genomes. Millstone is open source and easily deployable to a cloud platform, local cluster, or desktop, making it a scalable solution for any lab.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1474-760X, 1474-7596eISSN: 1474-760XDOI: 10.1186/s13059-017-1223-1Titel-ID: cdi_doaj_primary_oai_doaj_org_article_8459d7a4fb44406887544a589bea7343
- Format
- –
- Schlagworte
- 60 APPLIED LIFE SCIENCES, Automation, BASIC BIOLOGICAL SCIENCES, Bioinformatics, Cloning, Collaboration, Computational Biology - instrumentation, Computer applications, Design, DNA sequencing, E coli, Experimental evolution, Genetic engineering, Genome, Genome engineering, Genome, Microbial - genetics, Genomes, Genomics, Genotype, Genotypes, High-Throughput Nucleotide Sequencing, Internet, Laboratories, Laboratory evolution, Microbial evolution, Mutation, Oligonucleotides, Oligonucleotides - genetics, Researchers, Science, Software, Synthetic biology, Synthetic genomics, Visualization, Whole-genome sequencing