Details

Autor(en) / Beteiligte

• Chuma, Idrissa S
• Batamuzi, Emmanuel K
• Collins, D Anthony
• Fyumagwa, Robert D
• Hallmaier-Wacker, Luisa K
• Kazwala, Rudovick R
• Keyyu, Julius D
• Lejora, Inyasi A
• Lipende, Iddi F
• Lüert, Simone
• Paciência, Filipa M D
• Piel, Alexander
• Stewart, Fiona A
• Zinner, Dietmar
• Roos, Christian
• Knauf, Sascha

Titel

Widespread Treponema pallidum Infection in Nonhuman Primates, Tanzania

Ist Teil von

• Emerging infectious diseases, 2018-06, Vol.24 (6), p.1002-1009

Ort / Verlag

United States: U.S. National Center for Infectious Diseases

Erscheinungsjahr

2018

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• We investigated Treponema pallidum infection in 8 nonhuman primate species (289 animals) in Tanzania during 2015-2017. We used a serologic treponemal test to detect antibodies against the bacterium. Infection was further confirmed from tissue samples of skin-ulcerated animals by 3 independent PCRs (polA, tp47, and TP_0619). Our findings indicate that T. pallidum infection is geographically widespread in Tanzania and occurs in several species (olive baboons, yellow baboons, vervet monkeys, and blue monkeys). We found the bacterium at 11 of 14 investigated geographic locations. Anogenital ulceration was the most common clinical manifestation; orofacial lesions also were observed. Molecular data show that nonhuman primates in Tanzania are most likely infected with T. pallidum subsp. pertenue-like strains, which could have implications for human yaws eradication.