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Liver Transplantation for Colorectal Liver Metastases: Current Management and Future Perspectives
Ist Teil von
International journal of molecular sciences, 2021-03, Vol.22 (6), p.3093
Ort / Verlag
Switzerland: MDPI
Erscheinungsjahr
2021
Quelle
MEDLINE
Beschreibungen/Notizen
Patients with nonresectable liver metastases from colorectal cancer have few therapeutic options and a dismal prognosis. Although liver transplantation for this indication has historically a poor reputation, recent advances in the field of chemotherapy and immunosuppression have paved the way to revisit the concept. New data have shown promising results that need to be validated in several ongoing clinical trials. Since liver grafts represent a scarce resource, several new tools are being explored to expand the donor pool for this indication. The purpose of this review is to present all current available data and perspectives about liver transplantation for nonresectable liver metastases from colorectal cancer.