Details

Autor(en) / Beteiligte

• WaÅaszek, Marta
• Serwacki, Piotr
• Cholewa, Zbigniew
• Kosiarska, Alicja
• ÅwiÄtek - Kwapniewska, Wioletta
• KoÅpa, MaÅgorza
• Rafa, Elżbieta
• SÅowik, Róża
• Nowak, Karolina
• RóżaÅska, Anna
• Wójkowska-Mach, Jadwiga

Titel

Ventilator-associated pneumonia in Polish intensive care unit dedicated to COVID-19 patients

Ist Teil von

• BMC pulmonary medicine, 2023-11, Vol.23 (1), p.1-443, Article 443

Ort / Verlag

London: BioMed Central Ltd

Erscheinungsjahr

2023

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Abstract Background Healthcare-Associated Infections (HAI) are most frequently associated with patients in the Intensive Care Unit (ICU). Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), led to ICU hospitalization for some patients. Methods The study was conducted in 2020 and 2021 at a hospital in southern Poland. The Healthcare-Associated Infections Surveillance Network (HAI-Net) of the European Centre for Disease Prevention and Control (ECDC) was used for HAI diagnosis. The aim of this case-control study was to retrospectively assess the epidemiology of HAIs in ICU patients, distinguishing between COVID-19 and non-COVID-19 cases. Results The study included 416 ICU patients: 125 (30%) with COVID-19 and 291 (70%) without COVID-19, p  < 0.05. The mortality rate was 80 (64%) for COVID-19 patients and 45 (16%) for non-COVID-19 patients, p  < 0.001. Ventilator-Associated Pneumonia (VAP) occurred in 40 cases, with an incidence rate density of 6.3/1000 patient-days (pds): 14.1/1000 pds for COVID-19 patients vs. 3.6/1000 pds for non-COVID-19 patients. Odds Ratio (OR) was 2.297, p  < 0.01. Acinetobacter baumannii was the most often isolated microorganism in VAP, with 25 cases (incidence rate 8.5%): 16 (18.2%) in COVID-19 patients vs. 9 (4.4%) in non-COVID-19 patients. OR was 4.814 (1.084–4.806), p  < 0.001. Conclusions Patients treated in the ICU for COVID-19 faced twice the risk of VAP compared to non-COVID-19 patients. The predominant microorganism in VAP cases was Acinetobacter baumannii.