Details

Autor(en) / Beteiligte

• Togashi, Kyo
• Yoneyama, Tohru
• Sutoh Yoneyama, Mihoko
• Yamamoto, Hayato
• Hatakeyama, Shingo
• Yoneyama, Takahiro
• Hashimoto, Yasuhiro
• Futagami, Masayuki
• Ohyama, Chikara

Titel

Renal metastasis of ovarian granulosa cell tumor

Ist Teil von

• IJU case reports, 2022-05, Vol.5 (3), p.186-190

Ort / Verlag

Australia: John Wiley & Sons, Inc

Erscheinungsjahr

2022

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Introduction We would like to present a rare case of metastatic renal tumor. Case presentation A 60‐year‐old woman presented to our department with a left renal tumor. She underwent a total hysterectomy and right adnexal resection for a stage IA ovarian granulosa cell tumor approximately 15 years ago, followed by left adnexal resection and postoperative chemotherapy with gemcitabine and paclitaxel 6 years ago. She received six courses of gemcitabine and carboplatin to treat a stage IC clear cell adenocarcinoma of the ovary. The patient was diagnosed with the left renal tumor and underwent a laparoscopic left nephrectomy. Immunostaining was positive for α‐inhibin and SF‐1 and showed FOXL2 402C→G (C134W) mutation. Finally, the patient was diagnosed with renal metastasis of a granulosa cell tumor. Conclusion To our knowledge, this is a very rare case of renal metastasis of a granulosa cell tumor with the FOXL2 mutation in an adult.