Details

Autor(en) / Beteiligte

• Rodrigues, Mariana Paiva
• Astoreca, Andrea Luciana
• Oliveira, Águida Aparecida de
• Salvato, Lauranne Alves
• Biscoto, Gabriela Lago
• Keller, Luiz Antonio Moura
• Rosa, Carlos Alberto da Rocha
• Cavaglieri, Lilia Renée
• Azevedo, Maria Isabel de
• Keller, Kelly Moura

Titel

In Vitro Activity of Neem ( Azadirachta indica ) Oil on Growth and Ochratoxin A Production by Aspergillus carbonarius Isolates

Ist Teil von

• Toxins, 2019-10, Vol.11 (10), p.579

Ort / Verlag

Switzerland: MDPI AG

Erscheinungsjahr

2019

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• is a saprobic filamentous fungus, food spoiling fungus and a producer of ochratoxin A (OTA) mycotoxin. In this study, the in vitro antifungal activity of neem oil (0.12% p/p of azadirachtin) was evaluated against the growth of six strains of and the production of OTA. Four different concentrations of neem oil were tested in addition to three incubation times. Only the concentration of 0.3% of neem oil inhibited more than 95% of the strain's growth (97.6% ± 0.5%), while the use of 0.5% and 1.0% of neem oil showed lower antifungal activity, 40.2% ± 3.1 and 64.7% ± 1.1, respectively. There was a complete inhibition of OTA production with 0.1% and 0.3% neem oil in the four strains isolated in the laboratory from grapes. The present study shows that neem essential oil can be further evaluated as an auxiliary method for the reduction of mycelial growth and OTA production.