Emerging infectious diseases, 2007-07, Vol.13 (7), p.1097-1100
2007
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Details
- Autor(en) / Beteiligte
- Titel
- Virus detection and monitoring of viral load in Crimean-Congo hemorrhagic fever virus patients
- Ist Teil von
- Emerging infectious diseases, 2007-07, Vol.13 (7), p.1097-1100
- Ort / Verlag
- United States: U.S. National Center for Infectious Diseases
- Erscheinungsjahr
- 2007
- Quelle
- Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
- Beschreibungen/Notizen
- We developed a real-time reverse transcription--PCR that detected 1,164 copies/mL of Crimean-Congo hemorrhagic fever virus per milliliter of serum at 95% probability (probit analysis) and was 100% concordant with nested PCR on 63 samples from 31 patients with confirmed infection. Infected patients who died appeared to have higher viral loads; low viral loads correlated with IgG detection.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1080-6040eISSN: 1080-6059DOI: 10.3201/eid1307.070068Titel-ID: cdi_doaj_primary_oai_doaj_org_article_74d36984090e4795bd8e4806da46eaee
- Format
- –
- Schlagworte
- 5′-nuclease assay, Care and treatment, Crimean-Congo hemorrhagic fever virus, Diagnosis, Dispatch, Genetic Variation, Hemorrhagic fever, Hemorrhagic Fever Virus, Crimean-Congo - classification, Hemorrhagic Fever Virus, Crimean-Congo - genetics, Hemorrhagic Fever Virus, Crimean-Congo - isolation & purification, Hemorrhagic Fever, Crimean - blood, Hemorrhagic Fever, Crimean - diagnosis, Hemorrhagic Fever, Crimean - mortality, Humans, Measurement, Phylogeny, Polymerase chain reaction, Reproducibility of Results, Reverse Transcriptase Polymerase Chain Reaction - methods, Reverse Transcriptase Polymerase Chain Reaction - standards, RT-PCR, Sensitivity and Specificity, Species Specificity, Viral Load, Viremia