Details

Autor(en) / Beteiligte

• Rasi-Bonab, Farnaz
• Jafari-Sales, Abolfazl
• Shaverdi, Mohammad Amin
• Navidifar, Tahereh
• Saki, Morteza
• Ghorbani, Atosa
• Adekanmbi, Abimbola Olumide
• Jafari, Behboud
• Naebi, Sara

Titel

Antibiotic resistance pattern and frequency of cagA and vacA genes in Helicobacter pylori strains isolated from patients in Tabriz city, Iran

Ist Teil von

• BMC research notes, 2021-05, Vol.14 (1), p.1-216, Article 216

Ort / Verlag

London: BioMed Central Ltd

Erscheinungsjahr

2021

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Helicobacter pylori is one of the most common causes of gastric infections in humans. It is estimated that approximately 50% of people around the world are infected with this bacterium. This study aimed to determine the antibiotic resistance pattern, as well as the frequency of cagA and vacA genes in H. pylori isolates obtained from patients in the clinical centers in Tabriz city, Iran. The culture method detected 100 (45.25%) H. pylori isolates from 221 biopsy samples during 3 years. The results showed that 63% and 81% of the isolates were positive for cagA and vacA genes, respectively. The highest resistance of isolates was seen against metronidazole (79%) and amoxicillin (36%), respectively. Also, the isolates showed the least resistance to tetracycline (8%).