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Update on Lynch syndrome genomics

Familial cancer, 2016-07, Vol.15 (3), p.385-393

Peltomaeki, Paeivi

2016

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Role of DNA Mismatch Repair Defects in the Pathogenesis of Human Cancer

Journal of clinical oncology, 2003-03, Vol.21 (6), p.1174-1179

Päivi Peltomäki

2003

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Mutations and epimutations in the origin of cancer

Experimental cell research, 2012-02, Vol.318 (4), p.299-310

Peltomaeki, Paeivi

2012

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Germline Mutation of RPS20 , Encoding a Ribosomal Protein, Causes Predisposition to Hereditary Nonpolyposis Colorectal Carcinoma Without DNA Mismatch Repair Deficiency

Gastroenterology (New York, N.Y. 1943), 2014-09, Vol.147 (3), p.595-598.e5

2014

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Epidemiological, clinical and molecular characterization of Lynch‐like syndrome: A population‐based study

International journal of cancer, 2019-07, Vol.145 (1), p.87-98

2019

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Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

Journal of clinical oncology, 2009-10, Vol.27 (28), p.4793-4797

2009

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Somatic mutation profiles as molecular classifiers of ulcerative colitis‐associated colorectal cancer

International journal of cancer, 2021-06, Vol.148 (12), p.2997-3007

2021

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Gene fusions and oncogenic mutations in MLH1 deficient and BRAFV600E wild-type colorectal cancers

Virchows Archiv : an international journal of pathology, 2022-04, Vol.480 (4), p.807-817

2022

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Oncogenic Potential of Bisphenol A and Common Environmental Contaminants in Human Mammary Epithelial Cells

International journal of molecular sciences, 2020-05, Vol.21 (10), p.3735

2020

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Desmoid tumor patients carry an elevated risk of familial adenomatous polyposis

Journal of surgical oncology, 2016-02, Vol.113 (2), p.209-212

2016

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Novel insights into tumorigenesis revealed by molecular analysis of Lynch syndrome cases with multiple colorectal tumors

Frontiers in oncology, 2024-04, Vol.14, p.1378392-1378392

2024

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Epigenetic signatures of familial cancer are characteristic of tumor type and family category

Cancer research (Chicago, Ill.), 2008-06, Vol.68 (12), p.4597-4605

2008

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Promoter-specific alterations of APC are a rare cause for mutation-negative familial adenomatous polyposis

Genes chromosomes & cancer, 2014-10, Vol.53 (10), p.857-864

2014

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BRAF mutation in sporadic colorectal cancer and Lynch syndrome

Virchows Archiv : an international journal of pathology, 2013-11, Vol.463 (5), p.613-621

2013

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Molecular changes preceding endometrial and ovarian cancer: a study of consecutive endometrial specimens from Lynch syndrome surveillance

Modern pathology, 2018-08, Vol.31 (8), p.1291-1301

2018

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Biallelic germline nonsense variant of MLH3 underlies polyposis predisposition

Genetics in medicine, 2019-08, Vol.21 (8), p.1868-1873

2019

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Methyltransferase expression and tumor suppressor gene methylation in sporadic and familial colorectal cancer

Genes chromosomes & cancer, 2015-12, Vol.54 (12), p.776-787

2015

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Converging endometrial and ovarian tumorigenesis in Lynch syndrome: Shared origin of synchronous carcinomas

Gynecologic oncology, 2018-07, Vol.150 (1), p.92-98

2018

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Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) Diagnostics

JNCI : Journal of the National Cancer Institute, 2007-02, Vol.99 (4), p.291-299

2007

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MicroRNA Methylation in Colorectal Cancer

Advances in experimental medicine and biology, 2016, Vol.937, p.109-122

2016

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LINE-1 hypomethylation in familial and sporadic cancer

Journal of molecular medicine (Berlin, Germany), 2012-07, Vol.90 (7), p.827-835

2012

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p53 Codon 72 and MDM2 SNP309 Polymorphisms and Age of Colorectal Cancer Onset in Lynch Syndrome

Clinical cancer research, 2005-10, Vol.11 (19), p.6840-6844

2005

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Altered methylation at microRNA-associated CpG islands in hereditary and sporadic carcinomas: a methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA)-based approach

Molecular medicine (Cambridge, Mass.), 2011-07, Vol.17 (7-8), p.726-735

2011

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Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis

Biomolecules (Basel, Switzerland), 2021-09, Vol.11 (10), p.1440

2021

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Detection of a major Lynch Syndrome-causing MLH1 founder variant in a large-scale genotyped cohort

Familial cancer, 2024-11, Vol.23 (4), p.647-652

2024

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Update on Lynch syndrome genomics

Role of DNA Mismatch Repair Defects in the Pathogenesis of Human Cancer

Mutations and epimutations in the origin of cancer

Germline Mutation of RPS20 , Encoding a Ribosomal Protein, Causes Predisposition to Hereditary Nonpolyposis Colorectal Carcinoma Without DNA Mismatch Repair Deficiency

Epidemiological, clinical and molecular characterization of Lynch‐like syndrome: A population‐based study

Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

Somatic mutation profiles as molecular classifiers of ulcerative colitis‐associated colorectal cancer

Gene fusions and oncogenic mutations in MLH1 deficient and BRAFV600E wild-type colorectal cancers

Oncogenic Potential of Bisphenol A and Common Environmental Contaminants in Human Mammary Epithelial Cells

Desmoid tumor patients carry an elevated risk of familial adenomatous polyposis

Novel insights into tumorigenesis revealed by molecular analysis of Lynch syndrome cases with multiple colorectal tumors

Epigenetic signatures of familial cancer are characteristic of tumor type and family category

Promoter-specific alterations of APC are a rare cause for mutation-negative familial adenomatous polyposis

BRAF mutation in sporadic colorectal cancer and Lynch syndrome

Molecular changes preceding endometrial and ovarian cancer: a study of consecutive endometrial specimens from Lynch syndrome surveillance

Biallelic germline nonsense variant of MLH3 underlies polyposis predisposition

Methyltransferase expression and tumor suppressor gene methylation in sporadic and familial colorectal cancer

Converging endometrial and ovarian tumorigenesis in Lynch syndrome: Shared origin of synchronous carcinomas

Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) Diagnostics

MicroRNA Methylation in Colorectal Cancer

LINE-1 hypomethylation in familial and sporadic cancer

p53 Codon 72 and MDM2 SNP309 Polymorphisms and Age of Colorectal Cancer Onset in Lynch Syndrome

Altered methylation at microRNA-associated CpG islands in hereditary and sporadic carcinomas: a methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA)-based approach

Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis

Detection of a major Lynch Syndrome-causing MLH1 founder variant in a large-scale genotyped cohort

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