Details

Autor(en) / Beteiligte

• Silva, Antônio Augusto Moura da
• Lima-Neto, Lídio Gonçalves
• Azevedo, Conceição de Maria Pedrozo E Silva de
• Costa, Léa Márcia Melo da
• Bragança, Maylla Luanna Barbosa Martins
• Barros Filho, Allan Kardec Duailibe
• Wittlin, Bernardo Bastos
• Souza, Bruno Feres de
• Oliveira, Bruno Luciano Carneiro Alves de
• Carvalho, Carolina Abreu de
• Thomaz, Erika Barbara Abreu Fonseca
• Simões-Neto, Eudes Alves
• Leite Júnior, Jamesson Ferreira
• Cosme, Lécia Maria Sousa Santos
• Campos, Marcos Adriano Garcia
• Queiroz, Rejane Christine de Sousa
• Costa, Sérgio Souza
• Carvalho, Vitória Abreu de
• Simões, Vanda Maria Ferreira
• Alves, Maria Teresa Seabra Soares de Brito E
• Santos, Alcione Miranda Dos

Titel

Population-based seroprevalence of SARS-CoV-2 and the herd immunity threshold in Maranhão

Ist Teil von

• Revista de saúde pública, 2020-01, Vol.54, p.131-131

Ort / Verlag

Brazil: Faculdade de Saúde Pública da Universidade de São Paulo

Erscheinungsjahr

2020

Link zum Volltext

Quelle

Elektronische Zeitschriftenbibliothek (Open access)

Beschreibungen/Notizen

• To estimate the seroprevalence of SARS-CoV-2 in the state of Maranhão, Brazil. A population-based household survey was performed, from July 27, 2020 to August 8, 2020. The estimates considered clustering, stratification and non-response. Qualitative detection of IgM and IgG antibodies was performed in a fully-automated Elecsys® Anti-SARS-CoV-2 electrochemiluminescence immunoassay on the Cobas® e601 analyzer (Roche Diagnostics). In total, 3,156 individuals were interviewed. Seroprevalence of total antibodies against SARS-CoV-2 was 40.4% (95%CI 35.6-45.3). Population adherence to non-pharmaceutical interventions was higher at the beginning of the pandemic than in the last month. SARS-CoV-2 infection rates were significantly lower among mask wearers and among those who maintained social and physical distancing in the last month compared to their counterparts. Among the infected, 26.0% were asymptomatic. The infection fatality rate (IFR) was 0.14%, higher for men and older adults. The IFR based on excess deaths was 0.28%. The ratio of estimated infections to reported cases was 22.2. To the best of our knowledge, the seroprevalence of SARS-CoV-2 estimated in this population-based survey is one of the highest reported. The local herd immunity threshold may have been reached or might be reached soon.