Details

Autor(en) / Beteiligte

• Marcolino, Milena S.
• Ziegelmann, Patricia K.
• Souza-Silva, Maira V.R.
• Nascimento, I.J.B.
• Oliveira, Luana M.
• Monteiro, Luanna S.
• Sales, Thaís L.S.
• Ruschel, Karen B.
• Martins, Karina P.M.P.
• Etges, Ana Paula B.S.
• Molina, Israel
• Polanczyk, Carisi A.
• Schwarzbold, Alexandre Vargas
• de Oliveira Maurílio, Amanda
• de Barros, Ana Lara Rodrigues Monteiro
• Scotton, Ana Luiza Bahia Alves
• Rodríguez-Morales, Alfonso J.
• dos Reis, Anderson Lacerda
• Moura Costa, André Soares
• de Oliveira, Argenil José Assis
• Farace, Bárbara Lopes
• da Silva, Carla Thais Cândida Alves
• Ramos, Carolina Marques
• Cimini, Christiane Corrêa Rodrigues
• de Carvalho, Cíntia Alcantara
• Silveira, Daniel Vitório
• Ponce, Daniela
• Kroger, Emanuele Marianne Souza
• Manenti, Euler Roberto Fernandes
• Lucas, Fernanda Barbosa
• Rodrigues, Fernanda d'Athayde
• Anschau, Fernando
• Botoni, Fernando Antonio
• Bartolazzi, Frederico
• Crestani, Gabriela Petry
• Nascimento, Guilherme Fagundes
• Noal, Helena Carolina
• Duani, Helena
• Vianna, Heloisa Reniers
• Guimarães, Henrique Cerqueira
• de Alvarenga, Joice Coutinho
• de Morais, Júlia Drumond Parreiras
• Rugolo, Juliana Machado
• Franco, Lara Monalyza Gonçalves
• Moreira, Leila Beltrami
• de Oliveira, Leonardo Seixas
• Pinheiro, Lílian Santos
• Pacheco, Liliane Souto
• Kopittke, Luciane
• de Souza Viana, Luciano
• de Moura, Luis Cesar Souto
• Santos, Luisa Elem Almeida
• de Souza Cabral, Máderson Alvares
• Souza, Maíra Dias
• Tofani, Marcela Gonçalves Trindade
• da Silveira, Marconi Franco
• de Melo Andrade, Marcus Vinicius
• Ferreira, Maria Angélica Pires
• Bicalho, Maria Aparecida Camargos
• Martins, Maria Auxiliadora Parreiras
• Lima, Maria Clara Pontello Barbosa
• Borges, Mariana Balbinot
• Canesso, Mariana de Braga Lima Carvalho
• Nogueira, Matheus Carvalho Alves
• de Figueiredo, Meire Pereira
• Guimarães Junior, Milton Henriques
• Almeida, Mychelle Stefany Santos
• de Sordi, Mônica Aparecida de Paula
• Sampaio, Natália da Cunha Severino
• de Oliveira, Neimy Ramos
• Vianna, Paulo Tarso Lima
• Andrade, Pedro Guido Soares
• Assaf, Pedro Ledic
• Oliveira, Rafael Fusaro Aguiar
• de Carvalho, Rafael Lima Rodrigues
• de Almeida, Rafaela dos Santos Charão
• Martins, Raphael Castro
• Valacio, Reginaldo Aparecido
• Cardoso, Ricardo Bertoglio
• Coelho, Ricardo Braga
• Pozza, Roberta
• Mourato, Rodolfo Lucas Silva
• Vieira, Rodrigo Costa Pereira
• de Abreu, Roger Mendes
• Silva, Rufino de Freitas
• Francisco, Saionara Cristina
• Guimarães, Silvana Mangeon Mereilles
• Araújo, Silvia Ferreira
• Oliveira, Talita Fischer
• de Vargas, Tatiana
• Fereguetti, Tatiani Oliveira
• Lage, Thalita Martins
• Diniz, Thulio Henrique Oliveira
• dos Santos, Veridiana Baldon

Titel

Clinical characteristics and outcomes of patients hospitalized with COVID-19 in Brazil: Results from the Brazilian COVID-19 registry

Ist Teil von

• International journal of infectious diseases, 2021-06, Vol.107, p.300-310

Ort / Verlag

Canada: Elsevier Ltd

Erscheinungsjahr

2021

Link zum Volltext

Quelle

Electronic Journals Library - Freely accessible e-journals

Beschreibungen/Notizen

• To describe the clinical characteristics, laboratory results, imaging findings, and in-hospital outcomes of COVID-19 patients admitted to Brazilian hospitals. A cohort study of laboratory-confirmed COVID-19 patients who were hospitalized from March 2020 to September 2020 in 25 hospitals. Data were collected from medical records using Research Electronic Data Capture (REDCap) tools. A multivariate Poisson regression model was used to assess the risk factors for in-hospital mortality. For a total of 2,054 patients (52.6% male; median age of 58 years), the in-hospital mortality was 22.0%; this rose to 47.6% for those treated in the intensive care unit (ICU). Hypertension (52.9%), diabetes (29.2%), and obesity (17.2%) were the most prevalent comorbidities. Overall, 32.5% required invasive mechanical ventilation, and 12.1% required kidney replacement therapy. Septic shock was observed in 15.0%, nosocomial infection in 13.1%, thromboembolism in 4.1%, and acute heart failure in 3.6%. Age >= 65 years, chronic kidney disease, hypertension, C-reactive protein ≥ 100mg/dL, platelet count < 100×109/L, oxygen saturation < 90%, the need for supplemental oxygen, and invasive mechanical ventilation at admission were independently associated with a higher risk of in-hospital mortality. The overall use of antimicrobials was 87.9%. This study reveals the characteristics and in-hospital outcomes of hospitalized patients with confirmed COVID-19 in Brazil. Certain easily assessed parameters at hospital admission were independently associated with a higher risk of death. The high frequency of antibiotic use points to an over-use of antimicrobials in COVID-19 patients.