Details

Autor(en) / Beteiligte

• Poldemann, Jenna J.
• Hinrichs, Benjamin H.
• Makramalla, Abouelmagd
• Ribera, Josep M.
• Josep M Ribera

Titel

Unique Presentation of Rosai-Dorfman Disease as Concomitant Appendiceal and Rectal Masses with IgG4-Positive Plasma Cells Diagnosed by Core Needle Biopsy

Ist Teil von

• Case reports in oncological medicine, 2020-10, Vol.2020, p.1-5

Ort / Verlag

New York: Hindawi

Erscheinungsjahr

2020

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Rosai-Dorfman disease (RDD), or sinus histiocytosis with massive lymphadenopathy, is a rare non-Langerhans cell histiocytosis. We report a case of a 69-year-old male with concurrent appendiceal and rectal masses who underwent CT-guided percutaneous biopsy. Histopathology confirmed a diagnosis of RDD with IgG4-positive plasma cells. It is believed to be a subset of RDD that shares similar features with IgG4-related disease suggesting some overlap of the two diseases. Because gastrointestinal RDD accounts for less than 1% of extranodal disease, it is important to recognize this entity in order to guide management. We review the presentation, diagnosis, and treatment of gastrointestinal RDD and discuss the possible overlap with IgG4-related disease.