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Small Molecule SARM1 Inhibitors Recapitulate the SARM1−/− Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate

Cell reports (Cambridge), 2021-01, Vol.34 (1), p.108588-108588, Article 108588

2021

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cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons

Experimental neurology, 2020-07, Vol.329, p.113252-113252, Article 113252

2020

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Studies to Assess the Utility of Serum Neurofilament Light Chain as a Biomarker in Chemotherapy-Induced Peripheral Neuropathy

Cancers, 2023-08, Vol.15 (17), p.4216

2023

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Effect of combined treatment with methylprednisolone and soluble Nogo-66 receptor after rat spinal cord injury

The European journal of neuroscience, 2005-08, Vol.22 (3), p.587-594

2005

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Novel Bicyclic Piperazine Derivatives of Triazolotriazine and Triazolopyrimidines as Highly Potent and Selective Adenosine A2A Receptor Antagonists

Journal of medicinal chemistry, 2004-12, Vol.47 (25), p.6218-6229

2004

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D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons

Science (American Association for the Advancement of Science), 1990-12, Vol.250 (4986), p.1429-1432

1990

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Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy

The Journal of clinical investigation, 2003-02, Vol.111 (4), p.507-514

2003

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Motor fluctuations in levodopa treated parkinsonian rats: relation to lesion extent and treatment duration

Brain research, 1994-10, Vol.662 (1), p.69-74

1994

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Synthesis of alkyne derivatives of a novel triazolopyrazine as A2A adenosine receptor antagonists

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.511-515

2005

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Differential patterns of regional c-Fos induction in the rat brain by amphetamine and the novel wakefulness-promoting agent modafinil

Neuroscience letters, 1998-01, Vol.241 (2), p.95-98

1998

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NMDA receptor blockade reverses motor response alterations induced by levodopa

Neuroreport, 1994-12, Vol.5 (18), p.2586-2588

1994

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Long‐acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model

Journal of pharmaceutical sciences, 2002-02, Vol.91 (2), p.371-387

2002

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Motor response complications and the function of striatal efferent systems

Neurology, 1993-12, Vol.43 (12 Suppl 6), p.S23

1993

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First Synthesis of Piperazine-derived [1,2,4]Triazolo[1,5-a]pyrazine as an Adenosine A2A Receptor Antagonist

Heterocycles, 2005-10, Vol.65 (10), p.2321

2005

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Substance P increases release of acetylcholine in the dorsal striatum of freely moving rats

Brain research, 1993-10, Vol.623 (2), p.189-194

1993

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Synthesis of alkyne derivatives of a novel triazolopyrazine as A 2A adenosine receptor antagonists

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.511-515

2005

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GABAA and GABAB receptors differentially regulate striatal acetylcholine release in vivo

Neuroscience letters, 1993-10, Vol.160 (2), p.126-130

1993

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Synthesis of alkyne derivatives of a novel triazolopyrazine as A(2A) adenosine receptor antagonists

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.511-515

2005

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Identification of insulin-like growth factor binding protein-2 as a biochemical surrogate marker for the in vivo effects of recombinant human insulin-like growth factor-1 in mice

The Journal of pharmacology and experimental therapeutics, 1997-04, Vol.281 (1), p.522

1997

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Region‐Specific Targets of p42/p44MAPK Signaling in Rat Brain

Journal of neurochemistry, 1998-02, Vol.70 (2), p.558-571

1998

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Reversal of levodopa-induced motor fluctuations in experimental parkinsonism by NMDA receptor blockade

Brain research, 1995-12, Vol.701 (1), p.13-18

1995

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Controls for Lesions of the Nigrostriatal Dopamine System

Science (American Association for the Advancement of Science), 1991-07, Vol.253 (5017), p.332-332

1991

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MK-801 prevents levodopa-induced motor response alterations in parkinsonian rats

Brain research, 1996-10, Vol.736 (1), p.202-205

1996

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Levodopa replacement therapy alters enzyme activities in striatum and neuropeptide content in striatal output regions of 6-hydroxydopamine lesioned rats

Brain research, 1991-06, Vol.552 (1), p.113-118

1991

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Palliative and prophylactic benefits of continuously administered dopaminomimetics in Parkinson's disease

Neurology, 1994-07, Vol.44 (7 Suppl 6), p.S15

1994

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Small Molecule SARM1 Inhibitors Recapitulate the SARM1−/− Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate

cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons

Studies to Assess the Utility of Serum Neurofilament Light Chain as a Biomarker in Chemotherapy-Induced Peripheral Neuropathy

Effect of combined treatment with methylprednisolone and soluble Nogo-66 receptor after rat spinal cord injury

Novel Bicyclic Piperazine Derivatives of Triazolotriazine and Triazolopyrimidines as Highly Potent and Selective Adenosine A2A Receptor Antagonists

D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons

Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy

Motor fluctuations in levodopa treated parkinsonian rats: relation to lesion extent and treatment duration

Synthesis of alkyne derivatives of a novel triazolopyrazine as A2A adenosine receptor antagonists

Differential patterns of regional c-Fos induction in the rat brain by amphetamine and the novel wakefulness-promoting agent modafinil

NMDA receptor blockade reverses motor response alterations induced by levodopa

Long‐acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model

Motor response complications and the function of striatal efferent systems

First Synthesis of Piperazine-derived [1,2,4]Triazolo[1,5-a]pyrazine as an Adenosine A2A Receptor Antagonist

Substance P increases release of acetylcholine in the dorsal striatum of freely moving rats

Synthesis of alkyne derivatives of a novel triazolopyrazine as A 2A adenosine receptor antagonists

GABAA and GABAB receptors differentially regulate striatal acetylcholine release in vivo

Synthesis of alkyne derivatives of a novel triazolopyrazine as A(2A) adenosine receptor antagonists

Identification of insulin-like growth factor binding protein-2 as a biochemical surrogate marker for the in vivo effects of recombinant human insulin-like growth factor-1 in mice

Region‐Specific Targets of p42/p44MAPK Signaling in Rat Brain

Reversal of levodopa-induced motor fluctuations in experimental parkinsonism by NMDA receptor blockade

Controls for Lesions of the Nigrostriatal Dopamine System

MK-801 prevents levodopa-induced motor response alterations in parkinsonian rats

Levodopa replacement therapy alters enzyme activities in striatum and neuropeptide content in striatal output regions of 6-hydroxydopamine lesioned rats

Palliative and prophylactic benefits of continuously administered dopaminomimetics in Parkinson's disease

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