Details

Autor(en) / Beteiligte

• Cheng, Jin-Xiang
• Ren, Jiafeng
• Qiu, Jian
• Jiang, Yingcong
• Zhao, Xianchao
• Sun, Shuyu
• Su, Changjun

Titel

Rapid eye movement sleep and slow wave sleep rebounded and related factors during positive airway pressure therapy

Ist Teil von

• Scientific reports, 2021-04, Vol.11 (1), p.7599-7599, Article 7599

Ort / Verlag

England: Nature Publishing Group

Erscheinungsjahr

2021

Link zum Volltext

Quelle

Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals

Beschreibungen/Notizen

• This study aimed to investigate the clinical characteristics and predictors of increased rapid eye movement (REM) sleep or slow wave sleep (SWS) in patients with obstructive sleep apnea (OSA) following positive airway pressure (PAP) therapy. The study retrospectively analyzed data from patients with OSA who underwent both diagnostic polysomnography (PSG) and pressure titration PSG at the Tangdu Hospital Sleep Medicine Center from 2011-2016. Paired diagnostic PSG and pressure titration studies from 501 patients were included. REM rebound was predicted by a higher oxygen desaturation index, lower REM proportion, higher arousal index, lower mean pulse oxygen saturation (SpO ), higher Epworth sleepiness score and younger age (adjusted R  = 0.482). The SWS rebound was predicted by a longer total duration of apneas and hypopneas, lower N3 duration, lower SpO nadir, lower REM proportion in diagnostic PSG and younger age (adjusted R  = 0.286). Patients without REM rebound or SWS rebound had a high probability of comorbidities with insomnia and mood complaints. Some parameters (subjective and objective insomnia, excessive daytime sleepiness, age and OSA severity) indicate changes in REM sleep and SWS between diagnostic and titration PSG tests. Treatment of insomnia and mood disorders in patients with OSA may helpful to improve the use PAP.