Details

Autor(en) / Beteiligte

• Ouedraogo, Henri Gautier
• Zoure, Abdou Azaque
• Compaoré, Tegwinde Rebeca
• Ky, Herve
• Zida, Sylvie
• Zingué, Dezemon
• Ouedraogo, Oumarou
• Soubeiga, Serge Théophile
• Sagna, Tani
• Dabiré, Charlemagne
• Kambiré, Dinanibè
• Zongo, Dramane
• Yonli, Albert Théophane
• Nikiema, Abdoul Rahamani
• Nezien, Désiré
• Bansé, Gnintassa Cyrille
• Bicaba, Brice Wilfried
• Perier, Sophie
• Sawadogo, Charles
• Yabre, Zakariya
• Sangare, Lassana

Titel

Evaluation of ten (10) SARS-CoV-2 rapid serological tests in comparison with WANTAI SARS-CoV-2 ab ELISA in Burkina Faso, West Africa

Ist Teil von

• Virology journal, 2023-03, Vol.20 (1), p.57-57, Article 57

Ort / Verlag

England: BioMed Central Ltd

Erscheinungsjahr

2023

Quelle

springer (창간호~2014)

Beschreibungen/Notizen

• The aim of this study was to evaluate the performance of ten (10) SARS-CoV-2 serological rapid diagnostic tests in comparison with the WANTAI SARS-CoV-2 Ab ELISA test in a laboratory setting. Ten (10) SARS-CoV-2 serological rapid diagnostic tests (RDTs) for SARS-CoV-2 IgG/IgM were evaluated with two (2) groups of plasma tested positive for one and negative for the other with the WANTAI SARS-CoV-2 Ab ELISA. The diagnostic performance of the SARS-CoV-2 serological RDTs and their agreement with the reference test were calculated with their 95% confidence intervals. The sensitivity of serological RDTs ranged from 27.39 to 61.67% and the specificity from 93.33 to 100% compared to WANTAI SARS-CoV-2 Ab ELISA test. Of all the tests, two tests (STANDARD Q COVID-19 IgM/IgG Combo SD BIOSENSOR and COVID-19 IgG/IgM Rapid Test (Zhejiang Orient Gene Biotech Co., Ltd)) had a sensitivity greater than 50%. In addition, all ten tests had specificity greater than or equal to 93.33% each. The concordance between RDTs and WANTAI SARS-CoV-2 Ab ELISA test ranged from 0.25 to 0.61. The SARS-CoV-2 serological RDTs evaluated show low and variable sensitivities compared to the WANTAI SARS-CoV-2 Ab ELISA test, with however a good specificity. These finding may have implications for the interpretation and comparison of COVID-19 seroprevalence studies depending on the type of test used.