Details

Autor(en) / Beteiligte

• Martora, Fabrizio
• Megna, Matteo
• Battista, Teresa
• Potestio, Luca
• Annunziata, Maria Carmela
• Marasca, Claudio
• Villani, Alessia
• Fabbrocini, Gabriella

Titel

Adalimumab, Ustekinumab, and Secukinumab in the Management of Hidradenitis Suppurativa: A Review of the Real-Life Experience

Ist Teil von

• Clinical, cosmetic and investigational dermatology, 2023-01, Vol.16, p.135-148

Ort / Verlag

New Zealand: Dove Medical Press Limited

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• To date, adalimumab (ADA) is the only biotechnology drug approved for the management of hidradenitis suppurativa (HS), an inflammatory skin condition. However, it quickly became apparent that the efficacy of adalimumab in daily practice was highly variable. In our review, we highlighted the current evidence from literature on the use of biologics in HS in a real-life setting, particularly adalimumab, secukinumab and ustekinumab. Data on the effectiveness and safety of biologic drugs in HS management have been analyzed. Even if the results are promising, more studies are needed. In our opinion, the armamentarium of drugs for HS management is increasing, and treatment will be based on a tailored-tail approach, minimizing the risk of adverse events. In this context, we want to point out the reported effectiveness and safety data concerning adalimumab, ustekinumab and secukinumab as well as ixekizumab.