Marine drugs, 2018-09, Vol.16 (9), p.319
2018
Details
- Autor(en) / Beteiligte
- Titel
- Lead Compounds from Mangrove-Associated Microorganisms
- Ist Teil von
- Marine drugs, 2018-09, Vol.16 (9), p.319
- Ort / Verlag
- Switzerland: MDPI AG
- Erscheinungsjahr
- 2018
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The mangrove ecosystem is considered as an attractive biodiversity hotspot that is intensively studied in the hope of discovering new useful chemical scaffolds, including those with potential medicinal application. In the past two decades, mangrove-derived microorganisms, along with mangrove plants, proved to be rich sources of bioactive secondary metabolites as exemplified by the constant rise in the number of publications, which suggests the great potential of this important ecological niche. The present review summarizes selected examples of bioactive compounds either from mangrove endophytes or from soil-derived mangrove fungi and bacteria, covering the literature from 2014 to March 2018. Accordingly, 163 natural products are described in this review, possessing a wide range of potent bioactivities, such as cytotoxic, antibacterial, antifungal, -glucosidase inhibitory, protein tyrosine phosphatase B inhibitory, and antiviral activities, among others.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1660-3397eISSN: 1660-3397DOI: 10.3390/md16090319Titel-ID: cdi_doaj_primary_oai_doaj_org_article_57664425fc634ab4948b60006a972e7a
- Format
- –
- Schlagworte
- Anti-Bacterial Agents - isolation & purification, Anti-Bacterial Agents - metabolism, Anti-Bacterial Agents - pharmacology, Antifungal Agents - isolation & purification, Antifungal Agents - metabolism, Antifungal Agents - pharmacology, Antineoplastic Agents - isolation & purification, Antineoplastic Agents - metabolism, Antineoplastic Agents - pharmacology, Antiviral agents, Antiviral Agents - isolation & purification, Antiviral Agents - metabolism, Antiviral Agents - pharmacology, Bacteria, Bacteria - metabolism, Bioactive compounds, bioactive natural products, Biodiversity, Biodiversity hot spots, Biological activity, Biological Factors - isolation & purification, Biological Factors - metabolism, Biological Factors - pharmacology, Biology, Cancer, Chemistry, Cytotoxicity, Drug Discovery, drug leads, Ecological distribution, Ecological niches, Ecosystem biology, Ecosystems, Endophytes, Endophytes - metabolism, Fungi, Fungi - metabolism, Fungicides, Genomes, Glucosidase, Glycoside Hydrolase Inhibitors - isolation & purification, Glycoside Hydrolase Inhibitors - metabolism, Glycoside Hydrolase Inhibitors - pharmacology, Lead compounds, mangrove microorganisms, Mangrove swamps, Mangroves, Metabolites, Microorganisms, Morphology, Natural products, Niches, Organic chemistry, Phosphatase, Physiology, Plants (botany), Plants - microbiology, Protein-tyrosine-phosphatase, Proteins, Receptor-Like Protein Tyrosine Phosphatases, Class 5 - antagonists & inhibitors, Review, Salinity, Secondary metabolites, Soil, Soil Microbiology, Soil microorganisms, Studies, Tyrosine, Wetlands, α-Glucosidase