Details

Autor(en) / Beteiligte

• Wang, Hansheng
• Wang, Lei
• Yu, Dan
• Luo, Guoshi
• Yang, Shuguo
• Liu, Yan
• Ren, Tao
• Wang, Meifang

Titel

Exudative pleural effusion caused by lung fluke infection: A practical diagnostic approach

Ist Teil von

• International journal of infectious diseases, 2023-10, Vol.135, p.8-11

Ort / Verlag

Canada: Elsevier Ltd

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• •Lung fluke infection is a rare etiology for exudative pleural effusion.•Eosinophilic pleural effusion or eosinophilic infiltration are characteristics.•Certain diet histories are important clues for lung fluke infection.•Positive intradermal tests for Paragonimus-specific antigens are reliable. Objectives: Pleural effusion caused by lung fluke is a rare etiology of exudative pleural effusion (EPE), which is often misdiagnosed or delayed. We aim to summarize the diagnosis and treatment course of EPE caused by lung fluke infection and put forward a practical diagnosis approach. Methods: We retrospectively analyzed the diagnosis and treatment of 14 cases of EPE caused by lung fluke infection diagnosed by enzyme-linked immunosorbent assay of serum antibodies or egg detection. Results: All patients (100%) with an absolute count of eosinophils in peripheral blood exceeded 0.5 × 109/l, and 10 patients (71.4%) had a history of special ingestion. Eosinophilic PE occurred in 11 patients (78.6%), pleural biopsy of medical thoracoscopic demonstrated eosinophils infiltration in nine patients (64.3%), and parasite eggs in one patient. All patients showed positive intradermal tests for Paragonimus-specific antigens and enzyme-linked immunosorbent assay of serum antibodies to Paragonimus. Conclusion: For patients with unexplained PE, lung fluke infection should be highly suspected when pleural fluid or pleural biopsy shows eosinophilic PE or eosinophils infiltration, especially for patients with certain diet history.