Details

Autor(en) / Beteiligte

• Du, Qiao
• Peng, Fang
• Xiong, Qing
• Xu, Kejin
• Yang, Kevin Yi
• Wang, Mingqiang
• Wu, Zhitian
• Li, Shanying
• Cheng, Xiaorui
• Rao, Xinjie
• Wang, Yuyouye
• Tsui, Stephen Kwok-Wing
• Zeng, Xi

Titel

Genomic Analysis of Amphioxus Reveals a Wide Range of Fragments Homologous to Viral Sequences

Ist Teil von

• Viruses, 2023-03, Vol.15 (4), p.909

Ort / Verlag

Switzerland: MDPI AG

Erscheinungsjahr

2023

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Amphioxus species are considered living fossils and are important in the evolutionary study of chordates and vertebrates. To explore viral homologous sequences, a high-quality annotated genome of the Beihai amphioxus ( beihai) was examined using virus sequence queries. In this study, 347 homologous fragments (HFs) of viruses were identified in the genome of beihai, of which most were observed on 21 genome assembly scaffolds. HFs were preferentially located within protein-coding genes, particularly in their CDS regions and promoters. A range of amphioxus genes with a high frequency of HFs is proposed, including histone-related genes that are homologous to the or domains of viruses. Together, this comprehensive analysis of viral HFs provides insights into the neglected role of viral integration in the evolution of amphioxus.