Details

Autor(en) / Beteiligte

• Wei, Zuwu
• Wu, Ming
• Li, Zuanfang
• Lin, Zhan
• Zeng, Jinhua
• Sun, Haiyan
• Liu, Xiaolong
• Liu, Jingfeng
• Li, Buhong
• Zeng, Yongyi

Titel

Gadolinium-doped hollow CeO2-ZrO2 nanoplatform as multifunctional MRI/CT dual-modal imaging agent and drug delivery vehicle

Ist Teil von

• Drug delivery, 2018-01, Vol.25 (1), p.353-363

Ort / Verlag

Philadelphia: Taylor & Francis

Erscheinungsjahr

2018

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Developing multifunctional nanoparticle-based theranostic platform for cancer diagnosis and treatment is highly desirable, however, most of the present theranostic platforms are fabricated via complicated structure/composition design and time-consuming synthesis procedures. Herein, the multifunctional Gd/CeO 2 -ZrO 2 /DOX-PEG nanoplatform with single nano-structure was fabricated through a facile route, which possessed MR/CT dual-model imaging and chemotherapy ability. The nanoplatform not only exhibited well-defined shapes, tunable compositions and narrow size distributions, but also presented a well anti-cancer effect and MR/CT imaging ability. Therefore, the Gd/CeO 2 -ZrO 2 /DOX-PEG nanoplatform could be applied for chemotherapy as well as dual-model MR/CT imaging.