Details

Autor(en) / Beteiligte

• Ingram, David G
• Arganbright, Jill M
• Paprocki, Emily
• Halpin, Kelsee L

Titel

Sleep Disorders in Children with Prader Willi Syndrome: Current Perspectives

Ist Teil von

• Nature and science of sleep, 2022-11, Vol.14, p.2065-2074

Ort / Verlag

Macclesfield: Dove Medical Press Limited

Erscheinungsjahr

2022

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Children with Prader-Willi syndrome (PWS) face a multitude of potential health challenges including life-threatening obesity, endocrinopathies, behavioral and emotional dysregulation, developmental delays, and sleep disorders. In the current perspective piece, we provide a focused review of the condition's etiology and clinical findings, as well as a more in-depth discussion of sleep disorders frequently associated with PWS. In particular, we highlight and discuss difficult clinical scenarios frequently encountered by the pediatric sleep physician caring for this patient population, including diagnosis and treatment of complex sleep-related breathing disorders, considerations for sleep apnea surgery, the interplay between growth hormone and sleep apnea, diagnostic challenges in hypersomnia/narcolepsy, and current and emerging therapies for hypersomnia/narcolepsy. Overall, although there are many areas that need further research, sleep disorders remain a fruitful target for improving quality of life of children with PWS and their families. Keywords: Prader-Willi syndrome, narcolepsy, growth hormone, sleep apnea