Details

Autor(en) / Beteiligte

• Vlachakis, Panayotis K
• Theofilis, Panagiotis
• Kachrimanidis, Ioannis
• Giannakopoulos, Konstantinos
• Drakopoulou, Maria
• Apostolos, Anastasios
• Kordalis, Athanasios
• Leontsinis, Ioannis
• Tsioufis, Konstantinos
• Tousoulis, Dimitris

Titel

The Role of Inflammasomes in Heart Failure

Ist Teil von

• International journal of molecular sciences, 2024-05, Vol.25 (10), p.5372

Ort / Verlag

Switzerland: MDPI AG

Erscheinungsjahr

2024

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Heart failure (HF) poses a significant world health challenge due to the increase in the aging population and advancements in cardiac care. In the pathophysiology of HF, the inflammasome has been correlated with the development, progression, and complications of HF disease. Discovering biomarkers linked to inflammasomes enhances understanding of HF diagnosis and prognosis. Directing inflammasome signaling emerges as an innovative therapeutic strategy for managing HF. The present review aims to delve into this inflammatory cascade, understanding its role in the development of HF, its potential role as biomarker, as well as the prospects of modulating inflammasomes as a therapeutic approach for HF.