Details

Autor(en) / Beteiligte

• Jiang, Junsheng
• Mao, Yueyan
• Wu, Jiabo
• Zhou, Qian

Titel

Relationship between hematological parameters and bronchopulmonary dysplasia in premature infants

Ist Teil von

• Journal of international medical research, 2023-07, Vol.51 (7), p.3000605231187802-3000605231187802

Ort / Verlag

London, England: SAGE Publications

Erscheinungsjahr

2023

Quelle

MEDLINE

Beschreibungen/Notizen

• Objective To evaluate the association between hematological parameters on the first day of life and bronchopulmonary dysplasia (BPD) in preterm infants. Methods This retrospective study involved all premature infants admitted to our neonatal intensive care unit from January 2017 to June 2022. BPD was diagnosed based on hypoxia exposure for ≥28 days. The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), platelet count (PLT), mean platelet volume (MPV), and platelet mass index (PMI) were compared between infants with and without BPD. Multivariate analysis was conducted to evaluate the association between hematological parameters and BPD. Results This study involved 124 premature infants (48 with BPD, 76 without BPD). The BPD group had a lower gestational age and lower weight. The NLR, MPV, and PLR were considerably higher and the PLT and MPI were lower in the BPD than non-BPD group. After adjusting for covariates, logistic regression analysis suggested that the NLR, PLT, and PMI were independent risk factors for BPD. Moreover, the receiver operating characteristic curve indicated that the NLR, PLT, and PMI were reliable predictors of BPD. Conclusion Our findings suggest that a higher NLR and a lower PLT and PMI on the first day may increase the risk of BPD.