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Antimicrobial Ellagitannin of Punica granatum Fruits
Ist Teil von
Journal of the Brazilian Chemical Society, 2002-09, Vol.13 (5), p.606-610
Ort / Verlag
Sociedade Brasileira de Química
Erscheinungsjahr
2002
Quelle
EZB Free E-Journals
Beschreibungen/Notizen
The ethyl acetate extract of Punica granatum fruits was fractionated by chromatographic techniques to afford the ellagitannin punicalagin. The substance was found to be active against methicillin-resistant Staphylococcus aureus strains and was identified by HPLC/UV and ¹HNMR. The antibacterial assays which guided the isolation of the tannin were conducted using the disc diffusion method. Minimum inhibitory concentration (MIC) was determined by the dilution method according to NCCLS (National Committee for Clinical Laboratory Standards) procedure.