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Background: There is a close relationship between the radiation dose and the image quality; so that increasing the radiation dose leads to an increase in the image quality. Methods: In this study, images of different thicknesses and filters were obtained by using Multidetector Computed Tomography (CT)-128 and Body mass measurement device-7 (BMMD-7) phantom scanner. The parameters of radiation dose, noise, spatial, and contrast resolution were monitored by the observers as well. Findings: As the slice thickness increased, the amount of spatial resolution at different radiation doses was not significantly different from that of the standard image. In addition, by changing the reconstruction filter, a similar behavior was observed for spatial resolution (P ˂ 0.05). Conclusion: CT operators have the task of selecting the appropriate slice thickness and reconstruction filter for each medical application. Therefore, the radiation dose can be reduced to a higher degree according to the image quality required for diagnosis.