BMC biology, 2011-04, Vol.9 (1), p.22-22, Article 22
2011
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Details
- Autor(en) / Beteiligte
- Titel
- Learning to live together: mutualism between self-splicing introns and their hosts
- Ist Teil von
- BMC biology, 2011-04, Vol.9 (1), p.22-22, Article 22
- Ort / Verlag
- England: BioMed Central Ltd
- Erscheinungsjahr
- 2011
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- Group I and II introns can be considered as molecular parasites that interrupt protein-coding and structural RNA genes in all domains of life. They function as self-splicing ribozymes and thereby limit the phenotypic costs associated with disruption of a host gene while they act as mobile DNA elements to promote their spread within and between genomes. Once considered purely selfish DNA elements, they now seem, in the light of recent work on the molecular mechanisms regulating bacterial and phage group I and II intron dynamics, to show evidence of co-evolution with their hosts. These previously underappreciated relationships serve the co-evolving entities particularly well in times of environmental stress.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1741-7007eISSN: 1741-7007DOI: 10.1186/1741-7007-9-22Titel-ID: cdi_doaj_primary_oai_doaj_org_article_42deb0071b0f4575bea423a06f4db12a
- Format
- –
- Schlagworte
- Animals, Bacteria - genetics, Bacterial Physiological Phenomena, Bacteriophages - physiology, Deoxyribonucleic acid, DNA, Evolution, Molecular, Genes, Genetic diversity, Genomes, Host-Pathogen Interactions, Humans, Introns, Models, Molecular, Mutualism (Biology), Parasites, Physiological aspects, Proteins, Review, RNA Splicing, Virus Physiological Phenomena, Viruses - genetics