Molecules (Basel, Switzerland), 2021-09, Vol.26 (18), p.5510
2021
Details
- Autor(en) / Beteiligte
- Titel
- Lipid-Based Nanocarrier System for the Effective Delivery of Nutraceuticals
- Ist Teil von
- Molecules (Basel, Switzerland), 2021-09, Vol.26 (18), p.5510
- Ort / Verlag
- Switzerland: MDPI AG
- Erscheinungsjahr
- 2021
- Link zum Volltext
- Quelle
- EZB Electronic Journals Library
- Beschreibungen/Notizen
- Nutraceuticals possess several health benefits and functions; however, most nutraceuticals are prone to degradation in the gastrointestinal environment and have poor bioavailability. Application of a novel carrier system is of increasing importance to overcome obstacles and provide efficient applicability. Lipid-based nanocarriers provide a large surface-to-mass ratio, enhanced intestinal absorption by solubilization in the intestinal milieu, intestinal lymphatic transport, and altering enterocyte-based transport. A critical overview of the current limitation, preparation, and application of lipid-based nanocarriers (liposomes and niosomes) and lipid nanoparticles (SLNs and NLCs) is discussed. Physical and gastrointestinal stability and bioavailability of nanoencapsulated nutraceuticals are considered as well.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1420-3049eISSN: 1420-3049DOI: 10.3390/molecules26185510Titel-ID: cdi_doaj_primary_oai_doaj_org_article_41dee1c1b9c8458b90d0f9920636c65d
- Format
- –
- Schlagworte
- Administration, Oral, Bioavailability, Biological Availability, Dietary Supplements, Drug Carriers, Environmental degradation, Enzymes, Food, Functional foods & nutraceuticals, Humans, Intestinal absorption, Intestine, Lipids, liposomes, Metabolism, Nanoemulsions, Nanoparticles, niosomes, Permeability, physicochemical stability, polyphenols, Review, Small intestine, solid lipid nanoparticles, Solubilization, Stomach