Details

Autor(en) / Beteiligte

• Harris-Love, Michael O
• Avila, Nilo A
• Adams, Bernadette
• Zhou, June
• Seamon, Bryant
• Ismail, Catheeja
• Zaidi, Syed H
• Kassner, Courtney A
• Liu, Frank
• Blackman, Marc R

Titel

The Comparative Associations of Ultrasound and Computed Tomography Estimates of Muscle Quality with Physical Performance and Metabolic Parameters in Older Men

Ist Teil von

• Journal of clinical medicine, 2018-10, Vol.7 (10), p.340

Ort / Verlag

Switzerland: MDPI

Erscheinungsjahr

2018

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Estimates of muscle tissue composition may have greater prognostic value than lean body mass levels regarding health-related outcomes. Ultrasound provides a relatively low cost, safe, and accessible mode of imaging to assess muscle morphology. The purpose of this study was to determine the construct validity of muscle echogenicity as a surrogate measure of muscle quality in a sample of older, predominantly African American (AA) participants. We examined the association of rectus femoris echogenicity with mid-thigh computed tomography (CT) scan estimates of intra- and intermuscular adipose tissue (IMAT), basic metabolic parameters via blood sample analysis, muscle strength, and mobility status. This observational study was conducted at a federal medical center and included 30 community-dwelling men (age, 62.5 ± 9.2; AA, = 24; Caucasian, = 6). IMAT estimates were significantly associated with echogenicity ( = 0.73, < 0.001). Echogenicity and IMAT exhibited similar associations with the two-hour postprandial glucose values and high-density lipoproteins values ( < 0.04), as well as grip and isokinetic (180°/s) knee extension strength adjusted for body size ( < 0.03). The significant relationship between ultrasound and CT muscle composition estimates, and their comparative association with key health-related outcomes, suggests that echogenicity should be further considered as a surrogate measure of muscle quality.